Bethel Solomons (Auth.)'s A Synopsis of Skin Diseases PDF

By Bethel Solomons (Auth.)

ISBN-10: 1483167895

ISBN-13: 9781483167893

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D Y S T R O P H I C T Y P E . — V e s i c l e s o r bullae a p p e a r a n y w h e r e a f t e r t r a u m a , often becoming haemorrhagic. N i k o l s k y ' s s i g n is a b s e n t . H y p e r - or d e - p i g m e n t a t i o n , o r s c a r r i n g follows h e a l i n g . M u c o s a l lesions a r e b u l l o u s , i n f i l t r a t e d , o r l e u k o p l a k i c , a n d r a r e l y ulcerated. A t r o p h i c w h i t e p a t c h e s a r e left o n r e s o l u t i o n . Carcinoma develops rarely.

X E R O D E R M A P I G M E N T O S U M 33 D w a r f i s m a n d finger a n d t o e d e f o r m i t i e s m a y d e v e l o p . I t c h i n g is s o m e t i m e s p r e s e n t , a n d p o r p h y r i n u r i a m a y b e f o u n d . A t r i c h i a , microcephaly, acrocyanosis, a n d hyperidrosis are seen. T h e lethal dystrophic variety is v e r y r a r e , d e a t h o c c u r r i n g w i t h i n t w o m o n t h s of b i r t h . D i a g n o s i s . — B y i t s c o n g e n i t a l c h a r a c t e r a n d s i t e of l e s i o n s .

S y m m e t r i c a l d i s t r i b u t i o n is t h e r u l e . M u c o u s m e m b r a n e s a r e s o m e t i m e s affected. E y e e x a m i n a t i o n s h o w s a r e d d i s h - b r o w n b a n d in t h e o p t i c d i s k a r e a a n d s h i n y s t r e a k s a l o n g t h e vessels. H a e m o r r h a g e s o r e x u d a t e s m a y also b e n o t e d . Circulatory disturbances occurring a r e h y p e r t e n s i o n , i n t e r m i t t e n t c l a u d i c a t i o n , g a n g r e n e of e x t r e m i t i e s , calcification of vessels.

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A Synopsis of Skin Diseases by Bethel Solomons (Auth.)


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