By Kursad Turksen (Author)
This finished evaluate of our present figuring out of grownup stem mobile kinds and their legislation examines the derivation, characterization, and software of grownup stem cells present in skeletal muscle, dental pulp, prostate, kidney, the attention, internal ear, and different tissues. The authors pay designated realization to grownup stem cellphone plasticity and their application in basic tissue homeostasis, in addition to their functions in regenerative medication.
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Additional info for Adult Stem Cells
Int J Androl 23(Suppl. 2), 89–91. 28. Schrans-Stassen, B. H. G. , van de Kant, H. J. , de Rooij, D. , and van Pelt, A. M. M. (1999). Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogonia. Endocrinology 140, 5894–5900. 29. Brinster, R. , and Avarbock, M. R. (1994). Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci U S A 91, 11,303–11,307. 30. Brinster, R. , and Zimmermann, J. W. (1994). Spermatogenesis following male germ-cell transplantation.
Bjornson, C. , Rietze, R. , Reynolds, B. , Magli, M. , and Vescovi, A. L. (1999). Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 283, 534–537. 18 Slayton and Spangrude 42. Morshead, C. , Iscove, N. , and van der Kooy, D. (2002). Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med 8, 268–273. 43. Eglitis, M. , and Mezey, E. (1997). Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice.
Functional Test for Spermatogonial Stem Cells: Spermatogonial Stem Cell Transplantation The presence of spermatogonial stem cells or their functionality can be checked by the spermatogonial transplantation technique developed by Brinster and coworkers (29,30). In this technique, germ cells of one mouse are transplanted into the testes of a recipient mouse, the endogenous spermatogenesis of which is depleted by treatment with the alkylating agent busulfan. Also, mice carrying the Wv/Wv mutation can be used since their testes do not contain germ cells.
Adult Stem Cells by Kursad Turksen (Author)