Get Advances in Insect Physiology, Vol. 9 PDF

By J.E. Treherne

ISBN-10: 0120242095

ISBN-13: 9780120242092

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19). The most important aspect of the 5-HT-receptor interaction appears to be the formation of an electrostatic bond between the positively charged quartenary nitrogen atom at the end of the ethylamine side chain and an anionic site on the receptor. The specificity of the response depends on precise hydrophobic and hydrogen bonding involving the indole ring and its hydroxyl group with corresponding sites on the receptor. The perturbation induced in the receptor as a result of this 5-HT interaction is then translated into an increase in the concentration of two intracellular messengers.

And Matschinsky, F. M. (1967). Theophylline, epinephrine and neostigmine facilitation of neuromuscular transmission. Proc. natn. Acad. Sci. A. 57, 1893-1897. , Butcher, R. , Timms, A. R. and,Sytherland, E. W. (1 966). Effect of epinephrine on cyclic adenosine 3 ,5 -phosphate and hexose phosphates in intestinal smooth muscle. Biochim. Biophys. Acta. 115, 173-178. Bulbring, E. and Tomita, T. (1 970). Calcium and the action potential in smooth muscle. In “Calcium and Cellular Function” (A. W. ), pp.

BERRIDGE A N D W. T. PRINCE Epstein, S. , Levey, G. S . and Skelton, C. L. (1 97 1). Adenyl cyclase and cyclic AMP: biochemical links in the regulation of myocardial contractility. Circulation 43,437-450. Finder, A. , Boyme, T. and Schoemaker, W. C. (1 964). Relationship of hepatic potassium efflux to phosphorylase activation induced by glucagon. A m . J. Physiol. 206, 738-742. , Donald, R. A. and Butcher, R. W. (1969). Involvement of adenosine 3’,5’-monophosphate in release of ACTH. A m . J. Physiol.

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Advances in Insect Physiology, Vol. 9 by J.E. Treherne


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