By D. Virgil Alfaro III MD, Peter E. Liggett MD, William F. Mieler MD, Hugo Quiroz-Mercado MD, Rama D. Jager MD MBA FACS, Yasuo Tano MD
A popular crew of retina surgeons provides promising new advancements in age-related macular degeneration, with emphasis at the most vital advances some time past 5 years. content material addresses all features of administration, together with anatomy, body structure, and pathophysiology; imaging of the macula in age-related macular degeneration; prevention measures and remedy; remedy; and destiny instructions. Abundantly illustrated and beautifully equipped, this publication serves as a good reference and textbook.
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Extra resources for Age-related macular degeneration : a comprehensive textbook
99. Gottfired V, Davidi R, Acerbuj C, et al. In vivo damage to chorioallantoic membrane blood vessels by porphycene-induced photodynamic therapy. J Photochem Photobiol. 1995;30:115-121. 100. Lange N, Ballini JP, Wagnieres G, et al. A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV. Invest Ophthalmol Vis Sci. 2001;42:38-46. 22 101. Hammer-Wilson MJ, Akian L, Espinoza J, et al. Photodynamic parameters in the chick chorioallantoic membrane (CAM) bioassay for topically applied photosensitizers.
Under normal physiologic conditions, the pO2 at the inner portion of the photoreceptors approaches 0 mm Hg in the dark and somewhat higher in light. One possible reason for this design may be to lower the oxygen tension in the outer retina to decrease the amount of oxidative damage there, due to the inherently high susceptibility to oxidative damage conferred by the extraordinarily high proportions of both polyunsaturated fatty acids and retinoids in the outer segment membranes. In measurements of the constitutive secretion of VEGF in the eye, the RPE makes a prominent amount of VEGF (147).
Aust N Z J Ophthalmol. 1998;26:S56-S58. 65. Schweigerer L, Malerstein B, Neufeld G, et al. Basic fibroblast growth factor is synthesized in cultured retinal pigment epithelial cells. Bichem Biophys Res Commun. 1987;143:934-940. 66. Baudouin C, Fred-Reygrobellet D, Carvelle J-P, et al. Acidic fibroblast growth factor distribution in normal human eye and possible implications in ocular pathogenesis. Ophthalmic Res. 1990;22:73-81. 67. Connolly SE, Hjelmeland LM, LaVail MM. Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats.
Age-related macular degeneration : a comprehensive textbook by D. Virgil Alfaro III MD, Peter E. Liggett MD, William F. Mieler MD, Hugo Quiroz-Mercado MD, Rama D. Jager MD MBA FACS, Yasuo Tano MD